Cinnarizine Tablets

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Therapeutic Indication

Vertigo and balance disorders
Motion sickness prevention and treatment
Labyrinthine disorders (Meniere’s disease)
Adjunct therapy in cerebral circulatory disorders
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Cinnarizine

Tablet

Cinnarizine is an antihistamine and calcium channel blocker used to treat balance disorders, vertigo, and motion sickness. It works by reducing stimulation of the vestibular system and improving blood flow in the inner ear. Cinnarizine is widely prescribed for Meniere’s disease, labyrinthitis, and travel-related nausea.

Speciality Antihistamine & Calcium Channel Blocker
Tags Vertigo | Motion Sickness | Balance Disorder
Strength
  • 25 mg
  • 75 mg
Packing Size
  • 10 Tablets

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Mechanism

Cinnarizine blocks histamine H1 receptors and inhibits calcium influx in vascular smooth muscle. This reduces vestibular stimulation, improves cerebral and inner ear blood flow, and alleviates symptoms of vertigo and motion sickness.

Pharmacokinetics

  • Absorption: Well absorbed orally
  • Distribution: Widely distributed in tissues
  • Metabolism: Hepatic metabolism
  • Elimination: Renal excretion
  • Half-life: 3–6 hours

Side Effects

  • Drowsiness
  • Dry mouth
  • Weight gain (long-term use)
  • Gastrointestinal upset

Contraindication

  • Hypersensitivity to Cinnarizine
  • Parkinson’s disease (may worsen symptoms)

Interaction

  • Alcohol and CNS depressants (increase sedation)
  • Other antihistamines (additive effects)

Warning and Precautions

  • May cause drowsiness — avoid driving
  • Use cautiously in elderly patients
  • Monitor for extrapyramidal symptoms in long-term use